prescott-logo1

Investigating the
biophysical basis of computation
& the computational basis of pain

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People in the Lab *and personal haikus!

Principal Investigator

 

Committee meetings
Too many, make my brain numb  
Just like TTX.

steve 

Steven A. Prescott

Phone: 416-813-7654 x309094
Fax: 416-813-7717
E-mail: steve.prescott(at)sickkids.ca

Google Scholar profile

Research and Postdoctoral Associates

 

The name of the game
Is excitability  
For neurons and me.


Stephanie2017b

Stéphanie Ratté, Senior Research Associate

Stéphanie is contributing her experience in neuronal excitability to many of the projects in the lab. Her expertise includes optical methods and in vitro electrophysiology, especially dynamic clamp.

E-mail: stephanie.ratte(at)sickkids.ca

 

Sodium dances AP

Neuron sings a melody

And life is shining.

YuFeng2018

Yu-Feng Xie, Research Associate

Yu-Feng is investigating homeostatic changes in the excitability of DRG neurons.

E-mail: yufeng.xie(at)sickkids.ca

 

All models are wrong,

Except for mine. Wait, that's not

The saying. Oh well.

HeadshotScott

Scott Rich, Postdoctoral Fellow

Scott uses computational and mathematical techniques to understand how biophysical heterogeneity impacts the dynamics of neuronal microcircuits. His current work uses this perspective to study the influence of intracellular chloride concentrations on microcircuit oscillations.

E-mail: scott.rich(at)sickkids.ca

 

Students

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Nooshin Abdollahi, PhD Student

Nooshin is investigating the fundamental properties of axonal excitability.

E-mail: nooshin.abdollahi(at)sickkids.ca

 

The cell stops speaking
A bug in the neural code?
The model will tell.

 

 Laura

Laura Medlock, PhD Student

Laura uses multiscale modeling to investigate signal encoding in skin primary afferents and to explain how these touch signals are misprocessed in the spinal dorsal horn during chronic pain.

E-mail: laura.medlock(at)mail.utoronto.ca

   Chris Headshot

 

Christopher Dedek, PhD Student

Chris is studying the excitability of primary afferent terminals in the skin.

E-mail: christopher.dedek(at)sickkids.ca

 

 Can’t maintain balance?
Let me show you how its done
- I followed.

 AnkitHeadshot2

 

Ankit Roy, PhD Student

Ankit will investigate homeostatic regulation of intrinsic excitability and synaptic strength, and how that regulation is coordinated. 

E-mail: ankit.roy(at)sickkids.ca

 

Fast firing neurons
With prolonged input, rate slow
Precision maintained.

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Adel Halawa, MSc Student

Adel's project focusses the effects of adaptation in low-threshold mechanoreceptors during vibrotactile stimulation, including differential modulation of rate vs temporal coding. 

E-mail: adel.halawa(at)sickkids.ca

 

Spicy capsaicin,
Neurons scream "Ouch!" in chorus,
I can't eat spicy. 

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Kate Zhang, Undergraduate Student

Kate is studying the behavioural responses of mice following optogenetic activation of sensory afferents.

E-mail: katek.zhang(at)sickkids.ca

Technical Support

 

 

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Jason Jeong, Research Technologist

Jason ensures the lab is running smoothly by managing the animal colony, getting the supplies and equipment needed, and providing his skills with procedures and animal care to help with multiple projects.

E-mail: jason.jeong(at)sickkids.ca

 

Administrative Support


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Diana Arthurs, Administrative Assistant

Diana helps us with all administrative matters (HR, expenses, payroll, signatures, contracts, you name it!). 

E-mail: diana.arthurs(at)sickkids.ca

 

Past members

 


Jane2018b
Jane Yang
PhD student (2017-22)
Now Postdoc
at UCSD

SteveLesperance
Steve Lesperance
Postdoc (2016-22)
Now Science & Strategy
Analyst at Sixsense

MehdiHeadshot
Mehdi Azadgoleh
Research Assistant
(2021-22)

AaronHeadshot
Aaron Shifman
Postdoc (2020-21)
Now Scientist
at SocïVolta
 
 
Ket cropped
Dhekra Al-Basha
PhD Student (2015-21)
Read thesis here
Now Life Science Specialist
at L.E.K. Consulting
 
Abhinav Headshot
Abhinav Jindal
Project student (2020-21)
Now medical student

Abhinav Headshot
Amin Kamaleddin
PhD student (2016-2021)
 
 Russell main cropped
Russell Smith
Technologist (2014-20)
Now Ethics Coordinator
at U of T
 Ket cropped
Ket Hing Chong
Postdoc (2019-20)
Boriss2018
Boriss Sagalajev
Postdoc (2017-19)
Now Scientist at
Cologne University Hospital
Rose4Rose de Kort
Visiting MSc student (2018)
Now PhD student at
University of Maastricht
ArjunArjun Balanchadar
Medical student (2016-18)
Now neurology resident
at University of Toronto 
MIladMilad Lankarany
Postdoc (2014-18)
Now Scientist at Krembil
Research Institute 
Petri1Petri Takkala
PhD student (2013-18)
Now Postdoc at
William & Mary
blank2Dongyan Lin
Summer intern (2017)
Now PhD student
at McGill University
Blank4Emerson Grabke
Undergrad (2016-17)
Currently grad student
at University of Toronto
ShimaJessica Zung
Undergrad (2015-16)
Now PhD student
at Princeton
Picture HusainHusain Shakil
MSc Student (2015-16)
Now neurosurgery resident
at University of Toronto
 
kwanKwan Lee
Res Associate (2012-16)
Now Scientist
at Nevro
ShimaShima Shakory
Summer Intern (2013-15)
Now public health resident
at University of Toronto
DanielSigalDaniel Sigal
Summer Intern (2014)
blank3Bohan Xing
Summer Intern (2015)
Yi2Yi Zhu
Postdoc (2012-14)
Now Faculty at
Soochow University
AyahAyah Khubieh
Visiting MSc (2012-13)
Now a PhD student
at EPFL
Christina
Christina Lubinsky
Summer intern (2014)
Now registered nurse
at St. Michael's Hospital
in Toronto
Chris2
Chris Elder
Summer intern (2014)
Now Full Stack
Developer at Swift Medical
YoungAh
Young-Ah Rho
Postdoc (2011-12)
Now Research Scientist
at Virginia Tech
Nadine

Nadine S.-Weidenmaier

Lab Manager (2012-14)

Now at UCL

Sheliza
Sheliza Halani
Summer intern (2013)
Now internal medicine
resident at
University of Toronto
Adam
Adam Patterson
Summer intern  (2012-13)
Now neurology resident
at Nova Scotia Health
Authority
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Sergei Karnup
Res Associate (2011-12)
Now Res Associate
at U of Pittsburgh

BlankphotoLiz Brough

Lab Manager (2009-11)

blank5Gabriel Ocker
Rotating Student (2010)
Now a Scientist at
the Allen Institute
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Kerry Lazarus

Undergrad  (2009-10)